Acyl bromides
Selleck Chemical LLC Sepantronium Bromide (YM155) S1130-25mg
Sepantronium Bromide(YM155) is a potent survivin suppressant by inhibiting Survivin promoter activity with IC50 of 0 54 nM in HeLa-SURP-luc and CHO-SV40-luc cells does not significantly inhibit SV40 promoter activity but is observed to slightly inhibit the interaction of Survivin with XIAP YM155 down-regulates survivin and XIAP modulates autophagy and induces autophagy-dependent DNA damage in breast cancer cells Phase 2
Selleck Chemical LLC Umeclidinium bromide S3735-5mg
Umeclidinium bromide(GSK573719A) is a long-acting muscarinic antagonist approved for the maintenance treatment of chronic obstructive pulmonary disease (COPD)
Cayman Chemical N-a-Benzoyl-L-ArgInInamIdeh 5g
A synthetic nonapeptide sedative increases EEG delta activity and induces orthodox slow-wave sleep in free-moving rabbits at 30 nmol/kg i v increases NREM and total sleep in free-moving rats
Cayman Chemical p-Benzoyl-L-phenylalnIn 500mg
A polyether ionophore antibiotic selectively binds to monovalent cations over divalent cations active against Gram-positive bacteria (MICs 0 9-125 Ug/ml) reduces the viability of asexual and gametocyte P falciparum parasites (EC50s 1 3 and 14 8 nM respectively) reduces P berghei transmission in a mouse model of malaria at 4 and 8 mg/kg reduces the severity of lesions and completely protects chicks against mortality in a model of E tenella-induced coccidiosis at 5-10 ppm in the diet
Cayman Chemical p-Benzoyl-L-phenylalnIn 1g
Source Active recombinant human C-terminal His-tagged Bcl-2 expressed in E coli Amino acids MW 24 7 kDa
Cayman Chemical N4-benzoyl-2-DeoxycytIdIn 25g
A BD2 bromodomain inhibitor inhibits BD2 in BRD2 BRD3 and BRD4 (IC50s 0.08 0.05 and 0.02 UM respectively) and is selective for BD2 over BD1 (IC50s 3.76 2.34 and 1.16 UM for BRD2 BRD3 and BRD4 respectively) as well as CREBBP and p300 (IC50s 50 UM for both) decreases levels of the mRNAs encoding IL-6 and VCAM-1 in primary synovial fibroblasts isolated from patients with rheumatoid arthritis at 10 and 30 UM It prevents LPS-induced increases in IL-6 and Ifn-Y serum levels in a mouse model of LPS-induced endotoxemia at 75 mg/kg inhibits collagen-induced increases in ankle and knee diameter cartilage damage the ankle tissue levels of mRNAs encoding IL-1B Mmp-3 Mmp-13 and Rankl and ankle joint protein levels of IL-6 and VCAM-1 in a rat model of collagen-induced rheumatoid arthritis at 25 50 and 75 mg/kg twice per day improves gait and mobility and reverses body w8 loss as well as decreases the number of spinal cord inflammatory foci and apoptotic cells
Cayman Chemical N4-benzoyl-2-DeoxycytIdIn 10g
A BD2 bromodomain inhibitor inhibits BD2 in BRD2 BRD3 and BRD4 (IC50s 0.08 0.05 and 0.02 UM respectively) and is selective for BD2 over BD1 (IC50s 3.76 2.34 and 1.16 UM for BRD2 BRD3 and BRD4 respectively) as well as CREBBP and p300 (IC50s 50 UM for both) decreases levels of the mRNAs encoding IL-6 and VCAM-1 in primary synovial fibroblasts isolated from patients with rheumatoid arthritis at 10 and 30 UM It prevents LPS-induced increases in IL-6 and Ifn-Y serum levels in a mouse model of LPS-induced endotoxemia at 75 mg/kg inhibits collagen-induced increases in ankle and knee diameter cartilage damage the ankle tissue levels of mRNAs encoding IL-1B Mmp-3 Mmp-13 and Rankl and ankle joint protein levels of IL-6 and VCAM-1 in a rat model of collagen-induced rheumatoid arthritis at 25 50 and 75 mg/kg twice per day improves gait and mobility and reverses body w8 loss as well as decreases the number of spinal cord inflammatory foci and apoptotic cells
TARGETMOL CHEMICALS INC Pipecuronium bromide 10MG
Also available in 1 mg, 5 mg, 25 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. Pipecuronium bromide (RGH-1106) is a selective and potent nAChR antagonist that also acts as a non-depolarising steroidal neuromuscular blocker, causing muscle relaxation, often in conjunction with antibiotics. Purity 100%
Sigma Aldrich Fine Chemicals Biosciences Ipratropium bromide Relate5MG
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.for further information and support please go to the website of the issuing Pharmacopoeia.
Selleck Chemical LLC Butylscopolamine Bromide S2378-25mg
Butylscopolamine Bromide (Scopolamine Butylbromide (-)-Scopolamine butylbromide Hyoscine butylbromide) is a peripherally acting antimuscarinic anticholinergic agent used as an abdominal-specific antispasmodic
Sigma Organic Chemistry Titanium(IV) bromide | 25G | 7789-68-6 | MFCD00011265 | 0.98
Titanium(IV) bromide | 25G | 7789-68-6 | MFCD00011265 | 0.98
Sigma Organic Chemistry 4-(Chloromethyl)benzoyl chloride | 5G | 876-08-4 | MFCD00053224
CAS #: 876-08-4
MDL #: MFCD00053224
Purity: >97 %
UNSPSC Code: 12352100
Molecular Weight: 189.04
Apexbio Technology LLC Domiphen Bromide 538-71-6 10mM (in 1mL DMSO)
Domiphen bromide (CAS 538-71-6) is a small-molecule quaternary ammonium compound exhibiting antiseptic activity primarily through its function as a cationic surfactant Its positively charged molecular structure interacts with microbial membranes disrupting membrane integrity and leading to cell death Consequently it is widely studied for antimicrobial properties and applied in biological research as a surface-active disinfectant Domiphen bromide thus serves as a relevant tool compound in investigations focused on microbial control and antisepsis